Summer Institute (SCIM 1427)

Optimal Control
  applied to
Biological Models



Duration               : 15 - 18, 21 - 22 July 2014
Lectures               : 1:30 pm - 4:00 pm
Location               : Lady Shaw Building (LSB), Room 232B (LAB)


Course website: http://www.math.cuhk.edu.hk/~jwong/scim 1427


Instructor: Dr. Jeff Chak-Fu WONG
E-mail: jwong@math.cuhk.edu.hk
Office: Room 208, LSB
Phone extension: 2609 - 7987
Lecturer's office hours: Please e-mail me if you have any questions.

Lab helper:  Marco Chan
E-mail:  s1155031570@mailserv.cuhk.edu.hk

Lab helper:  Lam Ming-Fai
E-mail: s1155030985@mailserv.cuhk.edu.hk

 


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Aim

The problem will introduce the mathematical aspects of optimal control theory and apply it to biological models. These models are

1. mold and fungicide
2. bacteria
3. cancer
4. the epidemic model and
5. HIV treatment.

A basic knowledge of differentation and integral calculs is needed. Techniques on differential equations and computing programming are introduced, e.g., MATLAB is used.


References

Optimal Control Applied to Biological Models, 1st Edition  (c) 2007 by Suzanne Lenhart, John T. Workman, Boca Raton, Chapman & Hall/CRC.

Optimal Control Systems, 1st Edition  (c) 2003 by Desineni Subbaram Naidu, Boca Raton, CRC Press.

An Introduction to Optimal Control Problems in Life Sciences and Economics, 1st Edition (c) 2010 by Sebastian Anita, Viorel Arnautu, Vincenzo Capasso, Birkhauser.

Optimization: foundations and applications, 1st Edition (c) 2000 by Ronald E. Miller, Wiley.



Prerequisite

A basic knowledge of differentation and integral calculus is needed.



Format of the course




Course Schedule


Date
Topics
In Class Exercise
Take-Home Exercise
15 July  - Lecture 1
Basic Calculus Refresher

[Lecture note 1]

Characterization of maxima and minima for a function

[Lecture note 2]
[Lecture note 3]
[Lecture note 4]


 
[In-Class Exercise 1]
 


[In-Class Exercise 2]
[In-Class Exercise 3]
[In-Class Exercise 4]


 [Take Home 1]
16 July  - Lecture 2

Introduction to Ordinary Differential Equations

[Lecture note 5]

Introduction to MATLAB

[Lecture note 6]
[Lecture note 7]
 



[In-Class Exercise 5]



[In-Class Exercise 6]
 


[Take Home 2]

17 July  - Lecture 3 Calculus of Variations

[Lecture note 8]
 


[In-Class Exercise 7]


[Take Home 3]
18 July  - Lecture 4 Optimal Control

[Lecture note 9]
[Lecture note 10]
[Lecture note 11]



[In-Class Exercise 8]
[In-Class Exercise 9]
[In-Class Exercise 10]

 
[Take Home 4]
21 July  - Lecture 5
Numerical Solution of Optimal Control

[Lecture note 12]






[Take Home 5]
22 July  - Lecture 6
Biological Models

[Life Science Models]
[Lab Exercise 1]
[Lab Exercise 2]
[Lab Exercise 3]



 
 





Time Schedule

 

July 2014

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday



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